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Grade 3 or 4 neutropenia develops, consider dose delays, reductions, discontinuation, or G-CSF prophylaxis with subsequent doses. Diffuse Large B-Cell Lymphoma (DLBCL). Monitor for symptoms such as hypoesthesia, hyperesthesia, paresthesia, discomfort, a burning sensation, neuropathic pain, or weakness. Monitor patients for signs and symptoms of central nervous system abnormalities.
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